Lipoprotein Protocols

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Lipoprotein Protocols
Author : Jose M. Ordovas
Publisher : Humana Press
Release Date : 10 November 2010
ISBN : 1617370312
Pages : 284
File Size : 34,9 Mb
Total View : 9747 Views
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Lipoprotein Protocols by Jose M. Ordovas Book PDF Summary

The development of new methodologies has played a key role in the advancement of all areas of research. Specifically, the initial advances in our understanding of lipoprotein structure and metabolism were made possible by the development of ultracentrifugation and electrophoretic techniques. More recently, the advent of molecular biological techniques opened possibilities that were unthinkable just a few decades ago. The use of the analytical ult- centrifuge to study plasma lipoproteins began in the 1940s with the work of Mutzenbecher, McFarlene, Pedersen, Gofman, Lindgren, and Elliot. Another crucial step, during the 1950s, was the development of this tool as a prepa- tive technique by Havel, Eder, and Bragdon, among others. This technolo- cal progress allowed investigators to "dig" deeper into the structure of these complex macromolecules made of lipids and proteins, and permitted inves- gators to continue unraveling the physical and chemical characteristics of the proteins associated with lipoprotein particles (apolipoproteins) and the enzymes involved in their processing. This information led to both a better understanding of the biological functions of the lipoprotein fractions and their constituents, and creation of a more comprehensive overall scheme for plasma lipoprotein metabolism. Several gaps in this puzzle were filled through the work of Goldstein and Brown, who elucidated the structure and role of the low-density lipoprotein - ceptor. This was the first identified among a profusion of receptors that are key for the cellular catabolism of these particles.

Lipoprotein Protocols
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  • File Size : 54,9 Mb

The development of new methodologies has played a key role in the advancement of all areas of research. Specifically, the initial advances in our understanding of lipoprotein structure and metabolism were made possible by the development of ultracentrifugation and electrophoretic techniques. More recently, the advent of molecular biological techniques opened

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Lipoproteins and Cardiovascular Disease
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The lipid-rich and otherwise challenging nature of many key tissues complicates many aspects of current research, and applications of the unique nature of lipoproteins and their biological effects has engendered unique and vital methodologies. In Lipoproteins and Cardiovascular Disease: Methods and Protocols, experts in the field present a compendium of

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Apolipoproteins in Lipid Disorders
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There is increasing evidence for the clinicial value of the apo lipoprotein measurements. Besides cholesterol in plasma and li poprotein fractions, which is currently used as an indicator of cardiovascular risk, the measurement of the AI and B apolipopro teins can provide additional information about the patients' clinical status. Several

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Coronary Primary Prevention Trial
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Coronary Primary Prevention Trial written by famous author Anonim book pdf is ready to download and read online directly from your device. The book was released by Unknown in 1984 with total hardcover pages 284. Coronary Primary Prevention Trial Anonim book immediate popular and critical acclaim in Science genre.

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Lipoprotein Analysis
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Lipoproteins play an important role in maintaining the normal distribution of lipids in the body and in the transport of lipophilic compounds. They are also implicated, however, in some of the major diseases of the Western world including atherosclerosis, heart disease, and stroke. This has lead to a dramatic proliferation

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Handbook of Lipoprotein Testing
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Handbook of Lipoprotein Testing written by famous author Nader Rifai,G. Russell Warnick,Marek H. Dominiczak book pdf is ready to download and read online directly from your device. The book was released by Amer. Assoc. for Clinical Chemistry in 2000 with total hardcover pages 284. Handbook of Lipoprotein Testing Nader Rifai,

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Lipoprotein Protocols  Methods in Molecular Biology
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In Lipoprotein Protocols, Jose Ordovas compiles a cutting-edge collection of molecular protein techniques for studying advanced aspects of lipoprotein structure and metabolism. These step-by-step methods allow both the beginning and the advanced researcher to carry out not only fundamental, but also the most advanced genetic screening techniques, including RT-PCR and

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Flavoprotein Protocols
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As a scientist with an interest in proteins you will, at some time in your career, isolate an enzyme that turns out to be yellow—or perhaps you already have. Alternatively, you may identify a polypeptide sequence that is related to known flavin-containing proteins. This may, or may not, be

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